![]() Natural diuretics, such as caffeine, and prescription diuretics can also affect the kidneys. This class of drugs includes ibuprofen, naproxen, and aspirin. People should speak to their doctor about what their results mean.Ĭertain over-the-counter (OTC) painkillers, in particular, non-steroidal anti-inflammatory drugs (NSAIDs), can all adversely affect the kidneys. The ideal range of BUN values might vary based on the person’s age and the reference range that the laboratory uses. Changes in BUN levels also occur and during pregnancy.
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